Endocrinology, Diabetes, & Metabolism Consultants  
Our Provider(s)
George Thampy, MD

George Thampy, MD

Work Address
10004 Kennerly Road
Suite 160B
Saint Louis
MO, 63128

PhD, Kent State University, Kent, Ohio
MD, Saint Louis University School of Medicine, Saint Louis, MO

Post Doctoral Training
Internship and Residency: Saint Louis University Hospital, Saint Louis, MO

Fellowship in Endocrinology, Diabetes & Metabolism; Washington University School of Medicine, Saint Louis, MO.

Research Fellowships
Baylor College of Medicine, Houston, Texas

Licensure and Board Certification
Certified, American Board of Internal Medicine
Certified, American Board of Endocrinology, Diabetes and Metabolism.

Academic & Administrative Appointments
Clinical Assistant Professor, Division of Endocrinology
Saint Louis University School of Medicine, St. Louis, MO
Medical Director, Endocrinology and Diabetes

Hospital Appointments
Saint Anthony's Hospital, Saint Louis, MO

Memberships, Offices and Committee Appointments
Member, ADA
Member, AACE
Member, Board of Directors, ADA, Saint Louis Chapter
Member, The Endocrine Society
Member, ACP
Member, AMA

Other Professional Positions & Major Appointments
Previously, Major, United States Air Force Reserve

Research Interests
Diabetes, Insulin Resistance, Metabolic Syndrome and Obesity
see another section

Office Location(s):

Endocrinology, Diabetes, & Metabolism Consultants

10004 Kennerly Road
St. Anthony's Medical Building, Suite 160B
St. Louis, Missouri   63128
Location Phone: 314-842-1588
Location Fax: 314-543-5298

Original Publications
1 Thampy KG: Cholesteryl ester metabolism in rabbits - effect of cholesterol feeding and clofibrate treatment. Ph D Dissertation,Kent State University 1981;

2 Barnes EM,Jr., Thampy KG: Subclasses of adenosine receptors in brain membranes from adult tissue and from primary cultures of chick embryo. J Neurochem 1982;39:647-652.

3 Thampy KG, Barnes EM,Jr.: Adenosine transport by cultured glial cells from chick embryo brain. Arch Biochem Biophys 1983;220:340-346.

4 Thampy KG, Barnes EM,Jr.: Adenosine transport by primary cultures of neurons from chick embryo brain. J Neurochem 1983;40:874-879.

5 Thampy KG, Sauls CD, Brinkley BR, Barnes EM,Jr.: Neurons from chick embryo cerebrum: Ultrastructural and biochemical development in vitro. Dev Brain Res 1983;8:101-110.

*6 Thampy KG, Barnes EM,Jr.: gamma-Aminobutyric acid-gated chloride channels in cultured cerebral neurons. J Biol Chem 1984;259:1753-1757.

7 Thampy KG, Wakil SJ: Activation of acetyl-CoA carboxylase. Purification and properties of a Mn2+-dependent phosphatase. J Biol Chem 1985;260:6318-6323.

8 Jong YJ, Thampy KG, Barnes EM,Jr.: Ontogeny of GABAergic neurons in chick brain: studies in vivo and in vitro. Brain Research 1986;390:83-90.

9 Thampy KG, Wakil SJ: Role of protein phosphorylation in the regulation of acetyl-CoA carboxylase. Adv Prot Phosphatases 1986;3:257-270.

10 Tansey FA, Thampy KG, Cammer W: Acetyl-CoA carboxylase in rat brain. II. Immunocytochemical localization. Brain Research 1988;471:131-138.

11 Thampy KG, Huang WY, Wakil SJ: A rapid purification method for rat liver pyruvate carboxylase and amino acid sequence analyses of NH2-terminal and biotin peptide. Arch Biochem Biophys 1988;266:270-276.

12 Thampy KG, Wakil SJ: Regulation of acetyl-coenzyme A carboxylase. I. Purification and properties of two forms of acetyl-coenzyme A carboxylase from rat liver. J Biol Chem 1988;263:6447-6453.

13 Thampy KG, Wakil SJ: Regulation of acetyl-CoA carboxylase. II. Effect of fasting and refeeding on the activity, phosphate content, and aggregation state of the enzyme. J Biol Chem 1988;263:6454-6458.

14 Thampy KG: Formation of malonyl coenzyme A in rat heart. Identification and purification of an isozyme of acetyl coenzyme A carboxylase from rat heart. J Biol Chem 1989;264:17631-17634.

*15 Mabrouk GM, Helmy IM, Thampy KG, et al: Acute hormonal control of acetyl-CoA carboxylase. The roles of insulin, glucagon, and epinephrine. J Biol Chem 1990;265:6330-6338.

16 Thampy KG, Koshy AG: Purification of Carnitine Palmitoyltransferase from Heart Mitochondria by Hydrophobic Affinity Chromatography. Prot Exp and Purif 1990;1:177-183.

17 Thampy KG, Koshy AG: Purification, characterization, and ontogeny of acetyl-CoA carboxylase isozyme of chick embryo brain. Journal of Lipid Research 1991;32:1667-1673.

18 Thampy KG: Hypercholesterolemia of prolonged fasting and cholesterol lowering of re-feeding in lean human subjects. Scand J Clin Lab Invest 1995;55:351-357

19 Coburn SP, Thampy KG, Lane HW, Conn PS, Ziegler PJ, Costill DL, Mahuren JD, Fink WJ, Pearson DR, Schaltenbrand WE, Pauly TA, Townsend DW, LeBlanc AD & Smith SM: "Pyridoxic acid excretion during low vitamin B-6 intake, total fasting and bed rest. Am J Clin Nutr 1995;62:979-83

20 VanderWaal R, Thampy G, Wright WD, Roti Roti JL: Heat-induced modifications in the association of specific proteins with the nuclear matrix. Radiation Research 1996;145:746-753

21 Thampy KG, Haas MJ, Mooradian AD: Age-related changes in rat hepatic acetyl-coenzyme A carboxylase. Proc Soc Exp Biol Med (United States) 2000; 225(2) p123-7

22. Thampy KG, Haas MJ, Mooradian AD. Troglitazone stimulates acetyl-CoA carboxylase activity through a post-translational mechanism. Life Sci. 2000 Dec 29;68(6):699-708.

23. Coburn SP. Reynolds RD. Mahuren JD. Schaltenbrand WE. Wang Y. Ericson KL. Whyte MP. Zubovic YM. Ziegler PJ. Costill DL. Fink WJ. Pearson DR. Pauly TA. Thampy KG. Wortsman J. Elevated plasma 4-pyridoxic acid in renal insufficiency. Am J Clin Nutr 2002; 75(1):57-64